Note: Some courses run the entire semester (example: Fall 1 and 2), others run only part of the semester (example: Spring 2), and some courses last only a few weeks. Review course details below and read the syllabus for more information.
Fall elective courses
This course provides a comprehensive introduction to randomized controlled clinical trials. Topics include types of clinical trials research (efficacy and effectiveness trials), study design, treatment allocation, randomization and stratification, quality control, analysis, sample size requirements, patient consent, data safety and monitoring plans, reporting standards, and interpretation of results. Course activities: lectures, manuscript critiques, class project, and paper.
This course will introduce students to the most commonly used qualitative methods for health-related research and implementation science. It will provide a foundation in the application of qualitative methods to medical and health research. Topics addressed will include uses of qualitative data, designing studies, sampling strategies, collecting data, and qualitative analysis. A variety of methods will be discussed, with an emphasis on using focus groups and various interviewing techniques. Using case-based examples from active research studies, students will learn the best practices in qualitative research, how to plan and critically evaluate qualitative studies and articles, and fundamentals of writing strong qualitative aims for grant proposals. Upon completion of the course, students will be able to plan, propose, conduct, and analyze a qualitative study. Course activities are primarily discussion-based and include: case-based presentations, literature critique, and study development. All deliverables are purposefully designed to help a student walk through the steps of planning, proposing, and conducting qualitative research. Guest lectures by trained qualitative methodologists who are active qualitative researchers are included.
In this course, we will introduce students to the methods and applications of decision analysis and cost-effectiveness analysis in health care technology assessment, medical decision making, and health resource allocation. At the conclusion of the class, the student will have an understanding of the theoretical basis for economic evaluation and decision analysis, its application, and hands-on experience in the application of the methods. Among the topics covered are the development of a research question, choice of decision perspective, development of a decision analytic model, estimation of costs and benefits, use of preference based measures, addressing uncertainty and preparation of a manuscript presenting a decision analytic study.
Covid-19 Special Edition: The Covid-19 global and local crises have amplified many aspects of urgent healthcare issues and health inequalities related to global burden of diseases, including mortality and morbidity. The Fall 2020 Special Edition of the Global Burden of Disease course focuses on epidemiologic methods and global applications of GBD around the topics of Covid-19. The main topics include three major categories of global burden of diseases, including infectious diseases, chronic medical illnesses, and psychiatric & behavioral disorders. Topical areas include health care system, social determinants of health, and environmental justice. Focusing on the pandemic, students will learn basic methods used for global health research and major global, national and local trends; the impact of the pandemic on other disease patterns, morbidity and mortality; as well as learning about health care systems’ response, amplified health disparities, and environmental correlates and consequences. The transdisciplinary knowledge and hands-on skills in data visualization and analyses will deepen students’ understanding of future landscape of disease patterns and health care system; they will be able to apply the knowledge and skills to international or local health research and public health practice.
Winter elective course
A critical step in the dissemination of population-level clinical research is communicating research findings and key messages to the media and lay audiences. With conflicting messages coming from advocacy groups and others, the burden falls on the clinician-researcher to distill complex information, dispel misinformation, and tell a compelling story that resonates with the audience. The course will equip students with the skills, technique, experience and confidence needed to give successful, engaging media interviews and presentations related to the publication of research and expertise-specific topics. Through critique, tape and review exercises, class discussion, and guest speakers, students will learn all the facets that make an interview or presentation successful, including nonverbal communication and delivery skills (body language and vocal interpretation), content and messaging, and navigating interactions with the media. The instructor will evaluate each student’s skill set, on which the student will build throughout the course in a series of on-camera experiences.
Spring elective courses
This course will provide a comprehensive introduction to comparative effectiveness research. Topics include an overview of comparative effectiveness research, stakeholder engagement in comparative effectiveness research, designing comparative effectiveness research methodologic challenges in doing comparative effectiveness research, and recent developments in PCORI and Federal policy. Students will be expected to review and evaluate comparative effectiveness studies as well as actively participate in class discussions.
Course note: M19-501 and M21-560 are required prerequisites.
This course will provide a comprehensive introduction to principles of shared decision making and health literacy and their implications for clinical communication. Topics may include basic and applied research on shared decision making, principles of designing and evaluating patient decision aids, principles of health literacy, research on relationship between health literacy, numeracy, and health outcomes, best practices for communication with low-numerate and low-literate individuals, best practices (and controversies) in communicating probabilities and their associated uncertainty about screening and treatment outcomes, and best practices for designing and evaluating written information for clinical populations (such as intake forms, brochures, and informed consent documents). Course activities: lectures, manuscript critiques, class project, and paper.
This course introduces principles of patient safety, quality measurement and quality improvement. Classes are designed to provide students with hands-on skills in systems thinking and in preventing, learning from, and dealing with medical error and adverse events. Students will also learn fundamentals in approaches to evaluating quality, including quantitative methods in measure development. We will discuss various approaches and challenges to knowledge translation and effective change management in improving quality. Students will be encouraged to use their real-world experiences in problem solving around patient safety concerns, to develop and evaluate quality measures in their respective fields and to develop a quality improvement project in their area of interest as part of the course.
Introduction to the use of meta-analysis and related methods used to synthesize and evaluate epidemiological and clinical research in public health and clinical medicine. Concepts introduced and illustrated through case studies of public health and medical issues. Course activities: lectures, class discussion, group project, and paper.
Course note: M21-570 or equivalent required prerequisite.
This course will provide the knowledge and principles of predictive modeling, with applications to clinical and population health settings. Topics covered will include design, conduct, and application of risk predictions; statistical methods and analysis for model development and validation; evaluation of prediction models; emerging new methods; and risk stratification to identify a risk group, to assess eligibility to clinical trials and interventions, and to guide prevention priorities. The student will learn these topics through lecture, class discussions, data analysis lab, and homework.
Course note: Biostatistics I and II (M21-560 and M21-570) or equivalent required prerequisite.
The objective of this advanced graduate course is to prepare highly motivated students to perform health services research using administrative data. Lectures will provide tutorials on national administrative databases, review journal articles using these databases, instruction in SAS programming and application of health services research methods using administrative databases. Strengths and limitations of large databases that are commonly used for research will be considered, and special attention will be devoted to large federal databases that are readily available to new investigators. Students will learn how to obtain, link, and analyze large databases, understand the key issues related to data security and confidentiality, and become knowledgeable about key methodologic issues in observational studies using administrative data. Students will evaluate published studies based on large administrative databases, develop a health services research proposal and complete a short research project that uses administrative data.
Course note: You must contact the instructor two weeks prior to the start of class to discuss ideas for the class project; M19-501 and M21-560 are required prerequisites; SAS or SPSS software required. There is a $75 fee associated with this course to provide for access to the Center for Administrative Data (CADR) Linux server. This fee will cover the cost of access to data used in the course for homework assignments and the class project, and SAS statistical software on the server. To use SAS on the Linux server, students will also have to download SAS Enterprise Guide on their laptop or desktop computer (no extra charge for Enterprise Guide).
The objective of this course is to help students develop skills required to design research projects in the area of addiction science. This is accomplished by fostering a broad understanding of addiction and addictive behaviors in the population, spanning all levels of science from molecular genetics to drug policy. Students will be introduced to the epidemiology of substance use disorders and methods, including diagnostic criteria and their assessment, for in-depth understanding of surveys of substance use and associated disorders. Reviews and/or overviews of basic science aspects will include basic pharmacology, heritability and genetics, and genomic science. These concepts will then be related to more specialized topics, including comorbidity, treatment, recovery, and implementation research.
Course note: M19-501 Introductory Clinical Epidemiology, M19-511 Introductory Biostatistics, M19-510 Introduction to SAS; or equivalent; or course master approval. This is a required course for the Psychiatric and Behavioral Health Sciences Concentration
This course provides an overview to dissemination and implementation (D&I) science (i.e., translational research in health). Topics include the importance and language of D&I science; designs, methods and measures; differences and similarities across clinical, public health and policy settings; selected tools for D&I research and practice; and future issues. Course activities: Lectures, class discussions, manuscript critiques, and class project (culminating in a poster).
The purpose of the Independent Study course is to develop and refine the skills students learn in the fall core courses, Introductory and Intermediate Clinical and Epidemiology and Biostatistics series. Students enrolling in this course must come prepared with a circumscribed and well-defined project that relates to public health and population sciences. A research mentor within Washington University School of Medicine must be identified and approved of by MPHS leadership prior to the course enrollment. Objectives, a synopsis and milestones of the project per each student’s individualized syllabus should be identified and submitted to the MPHS leadership and mentor prior to the start of the semester. Students will be expected to submit a report, for example, drafted manuscript, an abstract for a conference, data analysis results, at the end of the spring semester to the MPHS leadership for credit. Course credit will be evaluated by both the research mentor and MPHS leadership. This two-credit course will be offered only as a pass/fail course to current MPHS students.
Course note: Prerequisites include approval from MPHS leadership and students must have completed the Introductory and Intermediate Clinical and Epidemiology and Biostatistics series. The course will meet on the first and last Friday of the Spring semester at 1-3pm, and students will present their independent study project. Also, A mid-term progress report is required. The Approval Form must be completed and approved by Dr. Yikyung Park prior to class registration.
This course is designed for medical students, clinicians, epidemiologists, and other public health researchers. The topics include basic statistical concepts and methods for continuous, categorical, count, and time-to-event data in multilevel and longitudinal settings. Through lectures, SAS/R/Stata lab, homework assignments, and a small project, students will understand the basic statistical concepts and methods for these types of data, will be able to address research questions using the concepts and methods, will be able to perform basic data analyses with one of SAS/R/Stata software, will be able to interpret the results in the context of clinical/epidemiological/public health research.
Course note: Prerequisites include: (1) M19-512 or knowledge of generalized linear model and Cox PHM. (2) introductory knowledge of SAS or R or Stata, and one of the software ready for the class.
This course designed to help students develop knowledge and skills required to design research projects in the area of digital-based psychiatric and behavioral health assessment and prevention interventions. The course focuses on learning and developing an innovative study using digital format including rapidly-changing mobile health (mHealth) technologies. The first segment of this course will review psychiatric disorder nosology, diagnostic assessment and screeners. The second segment will focus on examples and available resources. Third segment will introduce implementation and applications. The fourth segment will focus on social media platforms. Students will develop or analyze digitally-implemented group research projects.
Prerequisite: M19-501 Introductory Clinical Epidemiology or equivalent; or course master approval. This is a required course for the Psychiatric and Behavioral Health Sciences Concentration